NCI Well Connect Mid-Week Brief
September 16, 2015
Dear Steve, 

DID YOU KNOW that a study published this week in JAMA Internal Medicine linked the consumption of copious, daily amounts of olive oil with lower risk of breast cancer? One of our favorite nutrition researchers in the world, Dr. Miguel Martinez-Gonzalez authored the study. He is the doctor who has published four successful trials of The PaleoMediterranean Diet, an eating style that calls for, among other things, four tablespoons of olive oil daily!
Melatonin, Vitamin D Are Home Runs
Steve: Melatonin, a hormone that regulates the body's internal clock, is best know as a sleep aid. A new study in Cell shows that it may also give relief to patients with multiple sclerosis (MS), a debilitating neurological disorder that can quickly morph from remission into attacks that last days, months, or even years.

Researchers noticed that fewer MS flare-ups took place in the fall and winter-the time of year that melatonin production is at its peak.

Melatonin levels depend on sunlight exposure, so seasonal changes cause the hormone to fluctuate; less sunlight in the fall and winter increases melatonin, whereas more sunlight during spring and summer decreases it.

After monitoring MS patients for a year, they saw that during fall and winter, patients' relapse rates were 32% lower. Researchers believe it is a combination of the melatonin keeping rogue immune cells in check.

On the heels of a recent study showing how strongly vitamin D deficiency is related to the onset of MS, this has been quite a few weeks for MS prevention and treatment. And yet again, we see how important sleep is for our overall wellness!

Age-Related Macular Degeneration
A new study in JAMA Ophthalmology found that vitamin D deficiency may substantially alter the odds of developing age-related macular degeneration (AMD) in women with certain gene variants associated with an elevated AMD risk.

The increased risk may be greatest in those with the highest genetic risk for a specific variant in a protein called complement factor H (CFH). This is the first study to associate genetic AMD risk with vitamin D levels.

In addition, in this week's JAMA Neurology, a huge study found that low vitamin D status was associated with accelerated decline in cognitive function in ethnically diverse older adults. While this is one of many studies to come to this conclusion, it is in JAMA, which carries more weight in the medical community.

This is just two of the laundry list of reasons why you need to keep your vitamin D level within the normal range!
Simple Tip to Improve Your Cognition
This article is reserved for NCI Well Connect Members.
The Toxins You Accumulate Is All About How You Methylate
Bonnie and Steve: We are so excited to announce that one of the major nutritional conundrums which has evaded us, is no longer. We can now evaluate your complete methylation cycle, the most important pathway for detoxification of chemicals, hormones, and other unwanted environmental byproducts.

In the past, we have tried to cover all bases to help your metabolic pathway, but we did not have the entire map at our disposal. Now, we can pinpoint exactly if and where your metabolic cycle is impaired. Even better, we can fix it to make sure it is running smoothly.

Methylation is important for each and every one of us because the last thing we want is to have toxins recycling within our bodies with no way to escape. It can be carcinogenic, obesogenic, among many other adverse complications. 

The process takes 5 simple steps:
  1. Pay to have your genetic kit sent to your home from the lab 23andMe. You can get the test for $79.99 instead of $99 at this link because of your relationship with us. We have no financial interest in 23andMe.
  2. When you receive your genetic kit, follow the instructions to prepare your sample (saliva sample) and send back to 23andMe via the US Postal Service.
  3. 23andMe will email you when your results are complete.
  4. Download your raw data from 23andMe and and email the file to us. Contact us if you need help with this step.
  5. When we get your raw data file, we will upload it into our methylation database and contact you when the results are complete to make an appointment.
Why Is This Such an Incredible Opportunity?
  • In addition to the methylation data that we analyze, 23andMe maps your entire genome. This is crucial if we offer further genetic analysis on other bodily functions or for other health care providers who may require your genetic info.
  • You only need your genome mapped once! $79 is quite a deal.
  • 23andMe provides you with information about your ancestry. This is 23andMe's specialty. We do not delve into this aspect of your genetic results. It is completely private to you.
  • Many of you have heard us refer to the MTHFR genetic mutation for pregnancy, neurological function, and detoxification. MTHFR is included in the panel, as well as every other major gene associated with the methylation pathway.
Why Did We Decide to Finally Use Genetic Testing?
  • While we feel that much of the information about the humane genome is "not ready for prime time," we feel extremely confident that the genes associated with the methylation pathway have more than enough clinical data. The pharmaceutical industry has done most of the work for us by putting billions of dollars into researching genetics and methylation so they can find out who can best metabolize and avoid side effects from their drugs!
  • As better research comes along, having your genetic information allows us to contact you when, for instance, a genetic bone health panel comes along. How can you beat that service?
This may all seem overwhelming. As always, we are here to answer any questions you may have about the process.

Putting Your Methylation Results Into Practice

Going over the results should only take about 15 minutes. This is free for NCI Well Connect Members. For non-Well Connect members, the fee is $45.

To start the process, just go to 23andMe and click on the link: Then, let us know when your results are ready!
NCI Well Connect Membership
NCI Well Connect Membership is open to clients and non-clients.

One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Our eNewsletter has been awarded Constant Contact All Star status seven years in a row to date. Here is a recent preview issue.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 38 Action Plan titles to date on all aspects of wellness, including the new and improved How to Eat Healthy While Dining Out. You can view the full library of titles here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. Free 15 Minute Wellness Coaching Sessions on topics such as Immune System, Detox, Shedding Weight, Food Cravings and Food Addiction, or those of your own choosing.

The approximate cost for all of this? Less than one dollar a week!


Activate Your Membership Here!

Thirty years of serving your wellness needs. We appreciate your continued patronage and support.

Have a happy, healthy day,
Bonnie, Steve, Carolyn, Lilo, and Elizabeth
(847) 498 3422

M-F 9AM-5PM, SAT 9-4