NCI Well Connect Mid-Week Brief
October 21, 2015
Dear Steve, 

DID YOU KNOW that the International Osteoporosis Foundation's 2015 recommendations finally puts to bed the "protein is not good for older bones" theory. We have dispelled this myth for years. Finally, conventional bone experts have come around to our thinking.

The IOF document states, "To maintain physical function, older people need MORE dietary protein than do younger people." Moreover, they state, "Most older adults who have an acute or chronic disease need even more dietary protein." Or, as seen in the image above, broken nails can be from lack of adequate protein as well.

NOTE: 23andMe has increased the price of their genetic tests to $199 ($189 with our discount). The reason for the increase is the FDA just gave clearance for them to test consumers for genetic variants for 36 rare diseases that could be passed on to their offspring. The company will also provide data on certain "wellness" traits: caffeine consumption, lactose intolerance, alcohol flush reaction, and muscle composition.

This does not change our focus, which is at this time, getting your raw data and focusing on the methylation cycle. We will evaluate the research behind the new changes made by 23andMe, and will keep you posted on our findings. 
Lutein, Zeaxanthin and Eye Protection
Steve: A major, long-term study published in last week's JAMA Ophthalmology confirmed that a high intake of dietary components lutein and zeaxanthin is associated with a long-term reduced risk for advanced age-related macular degeneration (AMD).

This study is special for two reasons.
  1. All participants were free of disease at the start of the study.
  2. The participants were followed for 26 years. All studies on nutrient prevention should be structured this way. Unfortunately, few are.

When the researchers compared those with the highest blood lutein/zeaxanthin levels, they found an approximately 40% reduced risk for advanced AMD. Other carotenoids such as Beta Carotene were associated with a 25% to 35% lower risk of advanced AMD.


The researchers state that lutein and zeaxanthin form macular pigments that may protect against AMD by reducing oxidative stress, absorbing blue light, and stabilizing cell membranes. In addition, they suggest an association between genetic deficiencies related to lutein and zeaxanthin metabolism. Therefore, the more lutein and zeaxanthin you consume, the better chance you have to keep your genetic deficiencies quiet.
What Is Compulsive Exercise?
This article is reserved for NCI Well Connect Members.
Get Your 23andMe Results Yet?
Bonnie and Steve: The data is starting to roll in and the results have nothing been short of fascinating.

We have begun testing the methylation cycle derived from raw data provided by the genetics company 23andMe.

For many clients and their families, the results have reaffirmed why they have been so vigilant about managing their diets and lifestyles. They are keeping genetic deficiencies from expressing themselves negatively. For others, the results have provided the final push to reach their goals.

Interesting Factoid
Out of the clients that have we have screened so far, only one result has come back with zero genetic deficiencies.

We are finding that genetic screening for the methylation cycle is important for all ages, but especially for those in their fertility years.

The greatest thrill we get from this is that any genetic deficiency we test for now and in the future can be addressed with diet, nutrients, and lifestyle.

Why the Methylation Cycle? Why Now?
It was one of the major nutritional conundrums which had evaded us for years. We tried to cover all bases to help your methylation cycle, the most important pathway for detoxification of chemicals, hormones, and other unwanted environmental byproducts, but we did not have the entire map at our disposal. Now, we can pinpoint exactly if and where your cycle is impaired. Even better, we can fix it to make sure it is running smoothly.

Methylation is important for each and every one of us because the last thing we want is to have toxins recycling within our bodies with no way to escape. This can contribute to carcinogenesis, body mass gain, autoimmune disorders, to name a few.

The process takes 5 simple steps:
  1. Pay to have your genetic kit sent to your home from the lab 23andMe. You can get the test for $189 instead of $199 at this link because of your relationship with us. We have no financial interest in 23andMe.
  2. When you receive your genetic kit, follow the instructions to prepare your sample (saliva sample) and send back to 23andMe via the US Postal Service.
  3. 23andMe will email you when your results are complete.
  4. Download your raw data from 23andMe and and email the file to us. Contact us if you need help with this step.
  5. When we get your raw data file, we will upload it into our methylation database and contact you when the results are complete to make an appointment.
Why Is This Such an Incredible Opportunity?
  • In addition to the methylation data that we analyze, 23andMe maps your entire genome. This is crucial if we offer further genetic analysis on other bodily functions or for other health care providers who may require your genetic info.
  • You only need your genome mapped once! $189 is quite a deal.
  • 23andMe provides you with information about your ancestry, 36 rare disease traits, and certain wellness traits. We do not delve into this aspect of your genetic results at this time. It is completely private to you.
  • Many of you have heard us refer to the MTHFR genetic mutation for pregnancy, neurological function, and detoxification. MTHFR is included in the panel, as well as every other major gene associated with the methylation pathway.
Why Did We Decide to Finally Use Genetic Testing?
  • While we feel that much of the information about the humane genome is "not ready for prime time," we feel extremely confident that the genes associated with the methylation pathway have more than enough clinical data. The pharmaceutical industry has done most of the work for us by putting billions of dollars into researching genetics and methylation so they can find out who can best metabolize and avoid side effects from their drugs!
  • As better research comes along, having your genetic information allows us to contact you when, for instance, a genetic bone health panel comes along. How can you beat that service?
This may all seem overwhelming. As always, we are here to answer any questions you may have about the process.

Putting Your Methylation Results Into Practice

Going over the results should only take about 15 minutes. This is free for NCI Well Connect Members. For non-Well Connect members, the fee is $45.

To start the process, just go to 23andMe and click on the link: Then, let us know when your results are ready.

Those who have already done it are thankful that they did!
NCI Well Connect Membership
NCI Well Connect Membership is open to clients and non-clients.

One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Our eNewsletter has been awarded Constant Contact All Star status seven years in a row to date. Here is a recent preview issue.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 38 Action Plan titles to date on all aspects of wellness, including the new and improved How to Eat Healthy While Dining Out. You can view the full library of titles here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. Free 15 Minute Wellness Coaching Sessions on topics such as Immune System, Detox, Shedding Weight, Food Cravings and Food Addiction, or those of your own choosing.

The approximate cost for all of this? Less than one dollar a week!


Activate Your Membership Here!

Thirty years of serving your wellness needs. We appreciate your continued patronage and support.

Have a happy, healthy day,
Bonnie, Steve, Carolyn, Lilo, and Elizabeth
(847) 498 3422

M-F 9AM-5PM, SAT 9-4