NCI Well Connect Mid-Week Brief
February 10, 2016
Dear Steve, 

DID YOU KNOW that a study from this week's JAMA Neurology  links Proton Pump Inhibitors (PPIs), the blockbuster category of Acid Reflux/GERD medication, to higher risk of dementia?

From reading our eNewsletter, you are well aware that PPIs have a litany of side effects, but if you are still on them, this new discovery should give you the impetus to finally wean off of them.

In the conclusion of the study, the authors state, "the avoidance of PPI medication may prevent the development of dementia". Enough said.

Have a happy, healthy day. Steve and Bonnie
Foods Associated With Preventing Weight Gain and Inflammation
Steve and Bonnie: 
"Groundbreaking" Diet for Type 2 Diabetes
Australian government researchers have developed a "life­changing" diet and exercise program which they say has resulted in an average 40% reduction in medication levels for type 2 diabetes patients.

What's the secret? The plan incorporates an eating pattern that is very low in carbohydrates (especially grains and refined sugars) and higher in protein and unsaturated fats than is commonly prescribed.

The two year research intervention found greater improvements in the blood cholesterol profile, by increasing the levels of good (HDL) cholesterol, decreasing triglyceride levels, reductions in bad (LDL) cholesterol levels, reductions in the number and levels of blood glucose spikes and dips, and flattened the blood glucose profile over a 24­ hour period.

Not exactly groundbreaking to us because we know this, but great to see anyway!

Fruit, Veggies, and Weight
Eating more foods high in certain flavonoids help prevent weight gain over time for adults, according to a study in the January 27th issue of BMJ.

Researchers looked at seven flavonoid subclasses. People who ate more foods from specific flavonoid subclasses experienced less weight gain over time. Anthocyanins, flavonoid polymers, and flavonols had the greatest impact over four years.

Foods high in anthocyanins include dark red fruits like blackberries, red grapes, raspberries, cherries, blueberries, and strawberries, with the latter two fruits also high in flavonoid polymers, as are tea, pecans, and apples. Tea is also rich in flavonols, along with onions and some types of beans.

Antioxidants and Inflammation
Total dietary antioxidant capacity (TAC), partially driven by coffee consumption, significantly lowered endometrial cancer risk, according to a study in this month's Cancer, Causes, and Control.

Chronic inflammation is a central mechanism involved in cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases, the four leading causes of mortality. Diet is a major source of pro- and anti-inflammatory bioactive compounds. The Dietary Inflammatory Index (DII) was designed to estimate the overall inflammatory potential of the diet.

A study in this month's American Journal of Clinical Nutrition examined the association between the DII and mortality, as well as assess whether antioxidant supplementation could modulate this association.

The study was a randomized, double-blind, placebo-controlled trial in which participants received antioxidant supplements or a placebo from 1994 to 2002 and were followed through 2007. 

Not surprisingly, there was increased risk of all-cause and cancer mortality in the placebo group but not in the antioxidant-supplemented group, suggesting that antioxidants may counteract some of the proinflammatory effects in our diets.

Another study on supplements that followed subjects long-term!
Genetics Update
Steve: The research on genetics and nutrition are coming in tsunami waves. I will synthesize this data and share it with you periodically in a new Genetics Update column.

This column is reserved for NCI Well Connect Members.
Why Is This Graphic So Important?
Bonnie and Steve: If one or more of these boxes are yellow or red, then you have genetic deficiencies that may impair your ability to break down and move toxins from your body. The great thing is that you can prevent impairment with diet, lifestyle, and nutrient modification.

NCI Well Connect Membership
40% Off
One Year Membership Includes:
  1. Weekly eNewsletters (84 issues). We publish our long-form issue on Monday and a Mid-Week Brief on Wednesday. Here is a recent preview issue.
  2. Self-Help Action Plans. Access to two titles per month from our self-help Action Plan Library. There are currently 41 Action Plan titles to date on all aspects of wellness, including the new Fast Mimicking Diet Action Plan. You can view the full library of titles here.
  3. Natural Foods Shopping List. Updated quarterly, our Natural Foods Shopping List includes only the most meticulously vetted, highest quality food and beverage products that we recommend to our clients. These include gluten-free, corn-free, and kosher pareve items.
  4. Free 15 Minute Wellness Coaching Sessions (visits with Bonnie are separate) on topics such as 23andMe genetic results, Immune System, Detox, Shedding Weight, Food Cravings and Food Addiction, or those of your own choosing.

The approximate cost for all of this? Less than one dollar a week!


Activate Your Membership at 40% OFF Here!

Twinlab Quercetin + C on Long-Term Backorder
While this should not come as a surprise given the issues Twinlab has had keeping items in stock over the last 18 months, we have been notified by Twinlab that Quercetin + C in both sizes will not be available until August at the earliest. In addition, Twinlab Allergy C has been discontinued and will no longer be available.

To prevent these frequent occurrences, we are looking into the possibility of making our own Quercetin + C product, much like what we did with Alka Support. This process however, will take at least two to three months.

In the interim, we have individualized alternatives:

Pure Encapsulations Ester-C & Flavanoids
-Contains quercetin and rutin, both wonderful antinflammatory flavanoids that also enhance the action of vitamin C. A bit less quercetin than what was in the Twinlab.
-One capsule for one capsule exchange
-If taking for allergies, you can add extra, separate Quercetin during the height of the season.
-If taking for severe inflammation, then you can add one or two more Quercetin capsules.
-Ester-C is well tolerated for mild to moderate corn intolerants.

Pure Encapsulations Quercetin AND Ecological Formulas Vitamin C-1000 (tapioca source)
One to two capsules Quercetin AND only one vitamin C is necessary.

Metagenics Sinuplex
-Mirrors the old Twinlab Allergy Fighters the most.
-Cannot take if pineapple or shellfish sensitive.
We appreciate your continued patronage and support.

Have a happy, healthy day,
Bonnie, Steve, Carolyn, Lilo, and Elizabeth
(847) 498 3422

M-F 9AM-5PM, SAT 9-4