NCI Well Connect Mid-Week Brief
September 5, 2018
Dear Steve, 

DID YOU KNOW that a recent study in JAMA Neurology states that a gene associated with vitamin A metabolism was associated with an increased risk in Amyotrophic Lateral Sclerosis (ALS)?

Retinol-binding protein 4 (RBP4), a specific carrier for vitamin A but also expressed in fat tissue and found to be causally associated with insulin resistance, was lower in ALS cases than in those without ALS. Increasing RBP4 concentration was found to be associated with reduced odds for ALS. 

This is one of the reasons why we were so incessant in fighting the negative rhetoric about vitamin A over a decade ago. In addition, now that we can discern how one transfers beta carotene form food into usable retinol vitamin A, it is crucial not to overlook its importance.

PRODUCT UPDATES
NutriBiotic Dental Gel is on back order until the end of September. While it is out, we recommend: Magic Mud Charcoal Toothpaste (prepare for charcoal residue on the sink though) and Tom's of Maine Fluoride-Free Toothpaste Gel.

UP4 Daily has been discontinued. For an apples to apples replacement, we suggest Klaire Labs Probiotic Complex.

Have a happy, healthy day! Steve and Bonnie
 
News About Overweight and Obesity Vulnerability
Bonnie and Steve: According to authors of a study from the August issue ofProceedings of the National Academy of Sciences, clinicians need to consider how obesity is genetically intertwined with brain structure and mental performance.

Researchers found that people with higher a body mass index (BMI) showed reduced cognitive flexibility, reduced ability to delay gratification, reduced visuospatial ability and reduced verbal memory. They also found that people with increased BMI tended to have a thicker left prefrontal cortex and a thinner right prefrontal cortex. Previous studies have shown damage to the right prefrontal cortex can lead to increased eating.

Those with higher BMI also had increased volume in the left amygdala, which is believed to play a role in response to food cues. They also had decreased volume in the entorhinal-parahippocampal structures, which are associated with episodic memory and context mediation. This suggests people prone to obesity are more sensitive to visual food cues, and less able to resist them by considering the negative context of eating, like weight gain.

Many of the subjects were siblings, including fraternal and identical twins. This allowed researchers to determine the heritability of the traits as well as obesity, measured by BMI. Researchers found that many of the cognitive and neurological traits have genetic links with obesity.

Modifying neurobehavioral factors with cognitive training, to improve people's ability to resist food, for example, needs to be taken more seriously.

Our Pure Genomics panel includes a neurobehavioral profile that takes into account obesity and the mental genes it is intertwined with.
 
Gerolsteiner Alternative
Bonnie and Steve: We know that you love Gerolsteiner sparkling water. All of our family and staff love it too! However, there are some that do not care for Gerolsteiner, or find it cumbersome to purchase glass bottles.

We are delighted that Pure Encapsulations has launched Mineral2O, which is basically Gerolsteiner in "powder" form. Just add a tiny scoop to 8 oz. of water and that's it!

Here are some of the reasons why Mineral2O is so ideal:
  • It's portable. Much easier to bring with on vacations or to the gym. You can put a scoop into your water bottle and have an instant electrolyte water/mineral supplement.
  • The downside of a reverse osmosis filter is it removes all minerals. Also, if you live in a location with soft water, there are few minerals. Mineral2O can replace many of these for you.
  • Provides every essential electrolyte, but is very low in sodium. We get so much more sodium in our diets than all other electrolytes. You can add sea salt to your water if you need more sodium.
  • Perfect for athletes and those who exercise vigorously for before and after workouts/athletic events.
  • Better tolerated for those with absorption issues or chronic diarrhea.
  • When you have stomach flu or an intestinal virus that causes acute diarrhea, Mineral2O with a well tolerated sugar, such as maple syrup, could be awonderful alternative to the dehydration formulas that are loaded with corn and preservatives.
  • You could reduce your calcium and magnesium supplement intake. Consult with your health professional before doing so.
  • It's alkalizing. Along with calcium, magnesium, and chloride, Mineral2O contains 72 trace minerals, most of which are alkalizing.
Please direct any product questions by email to Steve.
 
Nutrient Helps Migraine Reduction 
This article is reserved for NCI Well Connect Members.

(continued)

Steve: A nutrient we recommend in our migraine protocol was recently confirmed yet again in research....

You can get this article by signing up for NCI Well Connect here today!
 
Genetic Wellness Screening 

Pure Genomics, our genetic wellness screening, covers 32 impeccably well-researched genes in seven categories:
  1. Methylation
  2. Vitamins and Minerals
  3. Detoxification
  4. Weight Management
  5. Cognitive Health and Memory
  6. Blood Sugar Balance
  7. Immune Health
Pure Genomics tips the balance toward optimal wellness. It only takes four simple steps to get started:
  1. Order a genetic kit from 23andme.com or Ancestry.com.
  2. Send your saliva sample back to 23andMe or Ancestry. They will email you when your results are ready.
  3. Download your raw genetic data file to your computer. Email us the data file.
  4. We generate your Pure Genomics report and contact you with the next step.
Email Steve for further questions or clarification.
 
NCI Well Connect Member Benefits 

One Year Membership Is Open to Clients and Non-Clients.
Membership Includes:
  1. Free 45 Minute Pure Genomics Screening & Consultation
     
  2. Twice Weekly eNewsletters. Long-form issue on Monday and mid-week brief on Wednesday.
     
  3. Self-Help Action Plans. Access to two titles per month from our 44 title self-help Action Plan Library. Full library of titles here.
     
  4. Natural Foods Shopping List. Meticulously vetted, high quality food and beverages we recommend to our clients. Gluten-free, corn-free, and kosher pareve items included. Updated quarterly.
We appreciate your continued patronage and support.

Need to search for information from past issues? Type in the word(s) in the google search box at this link.

Have a happy, healthy day,
stateofthebonnie

Bonnie, Steve, Carolyn, Lilo, Elizabeth, Sharron, and Lori
(847) 498 3422 
nutrocon@aol.com 
http://www.nutritionalconcepts.com

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