The number of Americans that will be diagnosed with Alzheimer’s disease (AD), and the cost associated with treating AD, will rise exponentially in the next 40 years. Research has shown that blood sugar disorders may be linked to AD, with some even calling AD “type 3 diabetes”.

Of the 103 published studies evaluated, 15 were chosen. The studies covered a variety of evidence, explaining detailed causes as well as preventive methods. The evidence reinforced the idea that blood sugar disorders are linked to AD, while the exact reasons have not all been confirmed. The evidence emphasized several preventive tools that can be implemented to mitigate the development of blood sugar related AD: exercise, melatonin, circadian rhythm, diabetes medications, iron metabolism, vitamin and mineral optimization, and diet. Public health professionals need to take note. The evidence also exhibited several limitations. Blood sugar disorders and their link to AD is still relatively new, so the length of most studies may not be sufficient to make a strong conclusion about the connection. In addition, because the genetic component linking blood sugar disorders to AD is so important, yet in its infancy still, caution needs to be taken before making conclusions.

Full research paper by Steve Minsky

DID YOU KNOW that consuming just one energy drink was associated with acute, significant impairment in endothelial function of young, healthy adults?

In findings from a new study presented at the American Heart Association Scientific Sessions 2018, researchers found an approximately 50% reduction in the arteries' ability to dilate.

The subjects weren't doing any physical activity, but many young people consume energy drinks before they exercise and during exercise, and it is critical that arteries dilate properly to deliver the increased demands of oxygen to the brain, heart, and muscles.

Statins Limit Your Ability to Fight Infection

Bonnie and Steve: When it comes to fighting infection, millions of Americans may eschewing one of their major defenses unknowingly.

In a study in Cell Host & Microbe, researchers examined the way methicillin-resistant Staphylococcus aureus (MRSA) delivers its deadly blow, and the way our body protects us. Unfortunately for those taking statin medication, a major line of defense may be deeply depleted.

When alerted of an invasion, immune cells first call macrophages to surround and engulf bacteria, quarantining them inside a compartment. The cell then destroys them with weapons called reactive oxygen species (ROS).

But many bacteria, including salmonella and MRSA, have found ways to avoid this form of attack. Until now, researchers did not know what backup system immune cells employed to fight these bacteria.

What they found is that while MRSA have learned to avoid the initial immune attacks for a while, it cannot hold them off forever. As long as immune cells can call upon mitochondria to ramp up the production of ROS, MRSA and the like will eventually succumb.

The problem with statin medication is that it depletes our mitochondria, which is why muscle pain and muscle wasting is a common side effect. We have also seen some research showing that in those taking statins, immune systems are often compromised. Now we know why.

NOTE: If you are immunocompromised or get infections often, and you are taking a statin, it may be having a devastating effect on your mitochondria, which provide your immune cells with the weapons to fight infection.

If you cannot eliminate the statin, at the very least, supplement with Co-enzyme Q10, which will help the remaining mitochondria function better.

Deep Dive Into Co-Enzyme Q10

Steve: CoQ10, or ubiquinone, is a vitamin-like substance found in nearly all cells in the human body. Sometimes called vitamin P, CoQ10 is a vital component of cellular energy metabolism and for proper functioning of the mitochondria...

You can get this article by signing up for NCI Well Connect here today!

NCI Well Connect eNewsletter - Free Version December 3, 2018

DID YOU KNOW that among the different mechanisms by which nutrients may exert their beneficial aging effects is the modulation of the hormonal anabolic levels? Undernutrition and anabolic hormonal deficiency frequently coexist in older individuals determining an increased risk of mobility impairment and other adverse outcomes. Mineral assessment is an important determinant of physical performance. In particular, there is evidence that magnesium exerts a positive influence on anabolic hormonal status, including testosterone, in men. A study in International Journal of Endocrinology confirmed the role of magnesium in testosterone bioactivity in men. In addition to magnesium, zinc and selenium also showed higher importance than other nutrients. These three nutrients should be well represented dietarily and supplementally to prevent or delay aging and the onset of disability. Magnesium Research Update Bonnie & Steve: As if you needed more research as to why magnesium is widely beneficial to so many... Magnesium deficiency in type 2 diabetes patients is directly associated with poor metabolic control. Therefore, focusing on augmentation of magnesium status and adequate magnesium intake in patients with type 2 diabetes is imperative, according to authors publishing in the August issue of Journal of the American College of Nutrition. According to a study in the August issue of British Journal of Nutrition, lower blood magnesium levels were associated with a higher risk of cardiovascular and all-cause mortality in the peritoneal dialysis population, especially among female patients.  Authors in a recent study in Neurology found that subjects presenting with intracerebral hemorrhage (ICH) had considerably lower magnesium levels. The data support the hypothesis that magnesium exerts a clinically meaningful influence on hemostasis in patients with ICH. Remember, to take advantage of magnesium's myriad benefits, you must supplement with the right source. Magnesium oxide will not exert a therapeutic effect because it is absorbed poorly. Oxide is great to use if you have constipation, however. Using an amino acid chelate, such as glycinate, is optimal to absorb and deliver to cells. Chiropractic Case Studies Chiropractic for anti-aging! Subluxation Research published a case study in June of 2018, where a patient's telomere length was measured before and after chiropractic care. After 36 visits the blood was retested and showed lengthening of the telomeres. This is exciting as according to an article in Pubmed anything that reduces the rate of telomere shortening helps to delay age-associated diseases and increase lifespan.  Did you know that normally telomere length shortens with age? This shortening increases the incidence of coronary heart disease, heart failure, diabetes, increased cancer risk and osteoporosis. Pubmed looked at the effects of smoking, diet and exercise to see what helps or hinders telomere length. Perhaps with the results of this case study you'll want to add consistent Chiropractic Care to the list of what helps lengthen your telomeres for a healthier and longer life.  Here is a synopsis of the Chiropractic case. The patient was a 35-year-old elementary school teacher who suffered for 5 years with neck and mid back pain as well as urinating at night. All of her symptoms started after being involved in a car accident. She had X-rays, which showed a loss of the normal curve of her neck as well as forward head posture, blood tests to determine her telomere length and her heart rate variability measurements indicated health risks. The patient received CBP® spinal care including Mirror Image® corrective spinal exercises, adjustments, and traction. After 36 visits she reported improvement in her urinating at night, neck and mid-back pain, and quality of life. The x-rays showed correction of her neck curve and forward head posture. The blood test showed significant improvement in her telomere length and the heart rate variability improved from a health risk to within normal limit.

Have a happy, healthy day! Steve and Bonnie

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