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Nutrients for Methylation, Aging

From eNewsletter 3/3/2021

DID YOU KNOW that the flavonoid quercetin is not only neuroprotective, but can actually stimulate the growth of new brain cells? According to a new study in Stem Cell Reports, two best of the best ways to generate brain cell production, which is especially necessary as we age, are exercise and quercetin. You may recall that one of quercetin's many attributes happens to be helping zinc enter the cell more effectively to fight viruses like SARS-CoV-2.

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NUTRIENTS FOR METHYLATION, AGING Steve and Bonnie: According to a profound study in Nutrients, micronutrients such as vitamins and trace elements are crucial for maintaining the health of all organisms. Micronutrients are involved in every cellular/biochemical process. They play roles in proper heart and brain functioning, influence immunological responses, and antioxidant defense systems. Therefore, prolonged deficiency in one or more micronutrients leads to cardiovascular or neurodegenerative disorders.

Keeping micronutrients at adequate levels is especially important as we age. We are prone to deficiencies due to age-associated functional decline. Moreover, lack of micronutrients has an indirect impact on the genome. Low levels reduce the activity of antioxidant enzymes, and therefore inhibit the efficiency of defense against free radicals which can lead to the formation of DNA lesions. The more DNA damage in the genetic material, the faster aging at the cellular level and a higher risk of pathological processes (for example, carcinogenesis or cancer).

Supplementation of crucial antioxidative micronutrients such as selenium, zinc, vitamin C, and vitamin E can positively influence the condition of an aging organism, including minimizing inflammation, enhancing antioxidative defense, and limiting the formation of DNA lesions. In consequence, it may lead to lowering the risk and incidence of age-related diseases such as cardiovascular diseases, neurodegenerative diseases, and malnutrition.

Another critical mechanism we can use to gauge how well we age is the state of our DNA methylation and how well we utilize B-vitamins. This can be viewed in our Pure Genomics screening. Routine serum lab data to gauge DNA methylation we can all get include albumin, alkaline phosphatase, creatinine, fasting glucose and hemoglobin A1c, percent lymphocytes, red cell distribution width, MCV and high-sensitivity C-reactive protein.

Much more exciting research on aging prevention to come!


PROSTATE, URINARY TRACT UPDATE This article is reserved for NCI Well Connect Members. You can get this article by signing up here. You can get our free eNewsletter by signing up at the top of our website.

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