This Sweetener Makes You Hungrier

From eNewsletter May 5, 2025

DID YOU KNOW that the artificial sweetener sucralose (Splenda) can make you hungrier?

A new study from Nature Metabolism found sucralose (Splenda) may increase activity in the brain’s hunger-regulating center (hypothalamus) compared to regular sugar, potentially stimulating appetite instead of satisfying it.

This action is very similar to how monosodium glutamate (MSG) tricks the brain and why, like sucralose, there are a litany of side effects.

To read the rest of today's issue, please go to this page.

Gut-Brain Connection | Sale Ending

From eNewsletter 4/30/2025

DID YOU KNOW that Cleveland Clinic funded a study of their employees to gauge the effectiveness of the influenza vaccine during the 2024-2025 respiratory viral season?

These are direct quotes from the pre-published study in Medrxiv:

"The cumulative incidence of influenza was similar for the vaccinated and unvaccinated states early, but over the course of the study the cumulative incidence of influenza increased more rapidly among the vaccinated than the unvaccinated. In an analysis adjusted for age, sex, clinical nursing job, and employment location, the risk of influenza was significantly higher for the vaccinated compared to the unvaccinated state, yielding a calculated vaccine effectiveness of −26.9%."

"Summary - Among 53402 working-aged Cleveland Clinic employees, we were unable to find that the influenza vaccine has been effective in preventing infection during the 2024-2025 respiratory viral season."

To read the rest of today's issue, please go to this page.

Mag, Yerba Mate | 40th Year Tribute

From eNewsletter 4/28/2025

DID YOU KNOW that Yerba Mate tea, the traditional South American beverage that we love recommending, has recently been flaunted by celebrities as an alternative to GLP-1 weight loss drugs?

Taking it a step further, a new study from Frontiers in Nutrition lists Yerba mate's metabolic effects across eight pathways: gut microbiota and hormonal signaling, hypothalamic appetite regulation, oxidative stress reduction, inflammation reduction, lipid metabolism reprogramming, glycemic regulation, mitochondrial efficiency, and neurotransmitter modulation.

Specifically, Yerba mate enhances GLP-1 secretion, restores leptin sensitivity via inflammation reduction, and boosts mitochondrial efficiency, yielding lower HbA1c, triglycerides, and adiposity (fat mass).

To read the rest of today's issue, please go to this page.