Thanksgiving Thoughts

From eNewsletter 11/24/2025

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Simple Sleep Solutions

From eNewsletter 11/19/2025

DID YOU KNOW that pyridoxal 5′-phosphate (activated vitamin B6) serves as the essential cofactor converting tryptophan into serotonin, which your body then transforms into natural melatonin? P-5-P also supports GABA synthesis for nervous system calming.

Thus, those with chronic sleep disturbance often respond to this form of vitamin B6 due to its impact on GABA and serotonin pathways. So instead of flooding your system with external hormones like melatonin, P-5-P can support your brain’s own sleep architecture.

The one drawback is that 50-100mg daily is usually needed for sleep enhancement, taken 30-60 minutes before bedtime. This amount can be contraindicated for many of you, so do not try this without discussing it with us or your physicians.

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Negative Melatonin Study

From eNewsletter 11/17/2025

DID YOU KNOW that gastrointestinal symptoms are frequently reported in children diagnosed with autism spectrum disorder?

A study from Autism followed gastrointestinal symptoms without a medical etiology in children with autism compared to similar aged participants with typical development starting at 2 and ending at age 12.

The children with autism presented with more gastrointestinal symptoms at each time point over the 10 year span, and they were also more likely to experience multiple and persistent gastrointestinal symptoms. The presence and number of gastrointestinal symptoms were associated with greater impairment in internalizing behaviors, sleep, communication, sensory processing, and repetitive behaviors.

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