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Maximize Exercise Success | Early Osteoporosis Intervention

From eNewsletter 6/30/2021

DID YOU KNOW that following a routine of regular physical activity combined with a diet including fruits, vegetables and other healthy foods may be key to middle-aged adults achieving optimal cardiometabolic health later in life, according to new research from Journal of the American Heart Association? Participants who followed the physical activity recommendations alone had 51% lower odds of metabolic syndrome. Participants who adhered to the dietary guidelines alone had 33% lower odds. Participants who followed both guidelines had 65% lower odds of developing metabolic syndrome.

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Steve and Bonnie: We have discussed ad nauseam the benefits of exercise for everyone. However, variability of the overall effectiveness of exercise depends upon many factors. A new study from Nature Metabolism echoes this, determining the specific types of exercise most likely to benefit a particular individual and identifying new therapeutic targets for diseases related to metabolism.

The variability in exercise response between any two individuals undergoing the very same exercise regimen is actually quite striking. For example, some may experience improved endurance while others will see improved blood sugar levels. Others may respond poorly to distance running while others thrive.

According to the researchers of this study, theirs is the first to assess an individual's baseline clinical profile to predict beforehand who is most likely to derive a significant cardiorespiratory fitness benefit from exercise training. This is not completely true because for several years, our Pure Genomics profile has allowed us to help predict this for our clients. But we digress.

The researchers measured the blood levels of approximately 5,000 proteins in 650 sedentary adults before and after a 20-week endurance exercise program. The research team then developed a protein score that improved their ability to predict an individual's trainability, or change in VO2max. For example, the score identified individuals who were unable to significantly improve their cardiorespiratory fitness despite participating in the standardized exercise program.

This roadmap to further explore potential interventions and provides an important step in individualizing exercise as a therapy. However, you presently have a roadmap at your fingertips: our Pure Genomics wellness screening. It is so important to know your genetic response to exercise because it can improve metabolic response, prevent unnecessary injury, and maximize athletic performance.


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