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Vit D2 or D3? | Glucosamine, Exercise, or Both?

From eNewsletter 5/25/2022

DID YOU KNOW that our favorite mineral magnesium, has frequently popped up in research lately? Optimal serum magnesium levels through diet and supplementation was associated with greater brain volumes and lower odds of cerebrovascular disease, according to a study in Nutrients. In patients with type 2 diabetes who underwent bariatric surgery, higher serum magnesium levels at surgery and 1-year following surgery were associated with better glycemic control and a greater likelihood of diabetes remission, according to a pre-print study published at medscape.com. As we've seen in numerous studies from different cultures, a Nutrients study examining the Chinese population concluded that magnesium deficiency was associated with a higher risk of insulin resistance and diabetes. Finally, a study in Nutrients suggests magnesium plays an important role in preventing metabolic disorders associated with obesity.

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Have a happy, healthy day! Steve and Bonnie Minsky

In Today's Issue...

  • Well Connect Feature: The Micronutrient Copper*

  • Public Health Alert

  • June, May 20% OFF Sale Items

  • Chiro Corner NEW!

  • Pure Genomics

  • Blog Briefs

  • Well Connect Member Benefits

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Public Health Alert

Steve: There are pressing public health matters other than COVID-19 you need to be aware of. We last posted an alert in early March. Antibiotics Treating babies with antibiotics in the first week of life is linked with a decrease in healthy bacteria necessary to digest milk and leads to an increase in antimicrobial resistance, according to a study in Nature Communications. Taking antibiotics in the first two years of life can prevent babies from developing a robust immune response to certain vaccines, according to a study in Pediatrics. Long-term antibiotic use in midlife is associated with small decreases in cognition assessed seven years later in women, according to a study in PLoS One. Ayurveda As we have warned you countless times over the years, be highly selective with any form of ayurvedic product you consume (such as ashwaganda), as they are often contaminated. A case report in Univadis explained one patient who got lead poisoning from short-term supplementation from an Ayurvedic (Indian) remedy. Cannabis Long-term cannabis use is linked to brain atrophy and poorer cognitive function in midlife. A large study from American Journal of Psychiatry showed long-term cannabis users had an 5.5 point IQ decline from age 18 to midlife, poorer learning and processing speed compared to childhood, and self-reported memory and attention problems. Long-term cannabis users also showed brain atrophy at midlife (age 45), which combined with mild midlife cognitive deficits, all known risk factors for dementia. Using cannabis alongside other drugs may come with a significant risk of harmful drug-drug interactions, according to new research from Drug Metabolism and Disposition. Cannabis can suppress Cytochrome P450s (CYPs) and UDP-glucuronosyltransferases (UGTs), two enzyme families that help metabolize and eliminate more than 70 percent of the most commonly used drugs from the body. Colorectal Cancer A recent study from International Journal of Cancer linked fecal immunochemical test (FIT) screening to improved long-term survival after a colorectal cancer diagnosis. The best survival outcomes were seen in patients who completed the noninvasive stool-based home screening within 12 months before diagnosis. Daycare Research from Applied and Environmental Microbiology reports a pediatric threat lurking within most in-door daycare centers: mold and yeast. These fungi are more common in indoor daycare centers than outside of them and may contribute mightily to rising adolescent chronic allergy and asthma rates. Hairdressers Hairdressers experience much more exposure to toxic agents than do consumers, putting them at much greater risk of hand eczema, according to Contact Dermatitis. Metformin Baby boys are at risk for genital defects if they were born to men who took the diabetes medication metformin during conception. The results from Annals of Internal Medicine suggest men with diabetes should advise their doctor on their use of metformin when trying to have a baby. Preeclampsia A glutathione genetic mutation that increased preeclampsia risk was ameliorated with supplemental vitamin C and/or reduced glutathione taken during pregnancy, according to a study in Journal of the American Heart Association. Proton Pump Inhibitors (PPIs) Long-term use of a PPI, used to treat reflux, was associated with an increased risk of type 2 diabetes in a Journal of Clinical Endocrinology & Metabolism study. The risk of diabetes increased from 19% to 56% as treatment duration increased from 8 weeks to more than 2 years, and prolonged treatment was associated with an even higher risk of diabetes in the youngest patients (age 40-65). Psilocybin Previous studies have shown that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants published in Journal of Psychopharmacology, the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients. Researchers in Nature Medicine think psilocybin fosters greater connections between different regions of the brain in depressed people, freeing them up from long-held patterns of rumination and excessive self-focus. Screen Time Before the pandemic, children aged 5 years and younger used screens for an average of approximately 25% of their waking hours. Now, 3 out of 4 children under the age of 2 are exceeding recommended screentime limitations, according to a study in JAMA Network. Guidelines from American Academy of Pediatrics, the World Health Organization, and several pediatric societies worldwide recommend completely avoiding screen time for children younger than 2 years (outside of video chatting). Vitamin D3 or D2? While this should not come as surprise to any of you, new research in Frontiers in Immunology has found significant differences between the two types of vitamin D, with vitamin D2 having a questionable impact on human health. Whereas vitamin D3 was found to balance people's immune systems and help strengthen defenses against viral infections such as COVID-19. We've said ad nauseam that prescription vitamin D2 is ineffective, and can potentially be harmful.


eNews Blog Briefs Glucosamine as Effective as Exercise?

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